Syrian hamsters are easy to tame, but may be nippy, particularly if handled during the day when they would normally be sleeping.
They tend to be a solitary animal and once they have reached 6 to 10 weeks of age they will not usually be happy to live with another hamster, with fighting a very real possibility. This fighting will be likely to occur during the night due to the nocturnal nature of hamsters and so could easily go unseen until serious injury occurs. Therefore the Syrian hamster is ideal if you are looking for a single pet, but if you wish to keep more than one then you should house them in separate cages in order to keep them happy and free of injury.
Due to their large size, you should be careful when buying cages and toys for Syrian hamsters as there may be small openings through which they could have difficulty squeezing. Hamster wheels also need to be large enough for them to use comfortably.